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Air-Tightness of printed circuit board

1487 1 Jan 03.2020, 17:23:56

Hi There!
I'm currently working on a new connection-panel for a samplestick of a cryostat; therefore I need to bring about 24-30 signals (coax) from a "vacuum" (~0.1-10mbar or 1ATM of He) to the outside world. 
As I would like to keep grounds seperate between the signals (-> star-ground next to the sample, down in the cryostat) the Connectors' ground should be isolated from its mount, however i've not seen vacuum-sealed isolated connectors. The other option is to use standard connectors (i.e. SMA) and have a isolating panel, but This option is not the greatest in terms of shielding.
So I had the following idea: Why not just use a PCB as interface panel, solder in PCB-mount connectors and connect the cabling on the inside. (here also a two-layer PCB with a groundplane on one side would serve as rather nice rf-shield) 
Now my question:
Is a standard FR-4 PCB air/He-tight? (at room temperature)

Any comments or questions are appreciated  

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